Glycosylation and Its Impact on Monoclonal Antibody Therapeutics: Enhancing Therapeutic Potential Through Glycan Engineering
Introduction Glycosylation is a imperative biochemical process that involves the attachment of carbohydrates to proteins, forming glycoproteins. This change plays a valuable role in plenty of biological functions, which include protein steadiness, folding, and cell interactions. In the context of monoclonal antibodies (mAbs), glycosylation noticeably affects their therapeutic efficacy. As researchers delve deeper into glycoengineering—an
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